When it comes to pregnancy termination, many individuals may prefer non-surgical options. One such method is Non Surgical Abortion Using Methotrexate. In this Women Centre's blog, we will explore what Methotrexate is, how it works, the procedure involved, its effectiveness, safety considerations, and post-treatment care.

What is Methotrexate?

Methotrexate is a medication originally developed to treat cancer, but it is also used in certain medical conditions, including ectopic pregnancies and non-surgical abortions. It is an antimetabolite that inhibits cell division and can cause the termination of early pregnancy.

How does Methotrexate work?

Methotrexate works by blocking the action of folic acid, which is essential for cell division. By inhibiting cell growth, the embryo cannot develop further, leading to the termination of the pregnancy.

The Procedure Of Non-Surgical Abortion Using Methotrexate

1. Consultation

The first step is to consult with a healthcare provider experienced in abortion procedures. They will assess your eligibility for a non-surgical abortion using Methotrexate based on factors such as gestational age, medical history, and contraindications.

2. Administration

 Methotrexate is administered either orally or by injection, depending on your specific situation and the healthcare provider's recommendation. The medication may be given once or in two doses, usually a few days apart.

3. Follow-up appointments

After the initial administration, follow-up appointments will monitor the progress of the abortion. These appointments may include blood tests to measure the levels of human chorionic gonadotropin, a hormone produced during pregnancy.

4. Completion of abortion

Most cases, the abortion process occurs within a week after Methotrexate administration. However, it can take longer; in some instances, additional treatment may be required, such as a surgical intervention.


The effectiveness of Methotrexate in terminating pregnancy varies depending on the gestational age. It is generally more effective during early gestation, up to seven weeks from the last menstrual period. Success rates range from 80% to 95%, with a higher success rate when the medication is administered earlier in the pregnancy.

Safety Considerations

While non-surgical abortion using Methotrexate is generally considered safe, discuss potential risks and complications with your healthcare provider. Some considerations include:

  1. Ectopic pregnancy: Methotrexate should not be used if an ectopic pregnancy is suspected, as it may be ineffective and potentially dangerous.
  1. Side effects: Common side effects may include nausea, vomiting, diarrhea, and abdominal pain. These symptoms usually subside within a few days.
  1. Emotional support: It is crucial to have emotional support during the abortion process, as it can be an emotionally challenging experience for some individuals.

Post-Treatment Care

After completing a non-surgical abortion using Methotrexate, your healthcare provider will provide instructions for post-treatment care. This may include:

  1. Follow-up appointments: It is important to attend scheduled follow-up appointments to ensure the abortion is successful and to monitor potential complications.
  1. Contraception: Discuss contraceptive options with your healthcare provider to prevent future unintended pregnancies.


Non Surgical Abortion Using Methotrexate provides an alternative option for individuals seeking pregnancy termination. It is a safe and effective method when performed within the appropriate gestational age and under the guidance of a healthcare provider. Always consult a qualified professional at the Women's Center to discuss your circumstances and ensure the best course of action.